Coversyl Arginine Adverse Reactions

Like all medicines, this medicine can cause side effects, although not everybody gets them.
Stop taking the medicinal product and see a doctor immediately, if the patient experiences any of the following side effects that can be serious: swelling of the face, lips, mouth, tongue or throat, difficulty in breathing (angioedema) (see "Precautions") (Uncommon - may affect up to 1 in 100 people); severe dizziness or fainting due to low blood pressure (Common - may affect up to 1 in 10 people); unusual fast or irregular heartbeat, chest pain (angina) or heart attack (Very rare - may affect up to 1 in 10,000 people); weakness of arms or legs, or problems speaking which could be a sign of a possible stroke (Very rare - may affect up to 1 in 10,000 people); sudden wheeziness, chest pain, shortness of breath, or difficulty in breathing (bronchospasm) (Uncommon - may affect up to 1 in 100 people); inflamed pancreas which may cause severe abdominal and back pain accompanied with feeling very unwell (Very rare - may affect up to 1 in 10,000 people); yellowing of the skin or eyes (jaundice) which could be a sign of hepatitis (Very rare - may affect up to 1 in 10,000 people); skin rash which often starts with red itchy patches on the face, arms or legs (erythema multiforme) (Very rare - may affect up to 1 in 10,000 people).
In decreasing order of frequency, side effects can include, tell the doctor if the patient notices any of the following side effects: Common (may affect up to 1 in 10 people): Headache, dizziness, vertigo, pins and needles, vision disturbances, tinnitus (sensation of noises in the ears), light-headedness due to low blood pressure, cough, shortness of breath (dyspnoea), gastro-intestinal disorders (nausea, vomiting, abdominal pain, taste disturbances, dyspepsia or difficulty of digestion, diarrhoea, constipation), allergic reactions (such as skin rashes, itching), muscle cramps, feeling of weakness.
Uncommon (may affect to 1 in 100 people): Mood swings, sleep disturbances, bronchospasm (tightening of the chest, wheezing and shortness of breath), dry mouth, angioedema (symptoms such as wheezing, swelling of the face, tongue or throat), intense itching or severe skin rashes, formation of blister clusters over the skin, kidney problems, impotence, sweating, an excess of eosinophils (a type of white blood cells), somnolence, fainting, palpitations, tachycardia, vasculitis (inflammation of blood vessels), photosensitivity reaction (increased sensitivity of the skin to sun), arthralgia (joint pain), myalgia (muscle pain), chest pain, malaise, oedema peripheral, fever, fall, change in laboratory parameters: high blood level of potassium reversible on discontinuation, low level of sodium, hypoglycaemia (very low blood sugar level) in case of diabetic patients, increased blood urea, and increased blood creatinine.
Rare (may affect up to 1 in 1000 people): Psoriasis worsening, Changes in laboratory parameters: Increased level of liver enzymes, high level of serum bilirubin.
Very rare (may affect up to 1 in 10,000 people): Confusion, cardiovascular disorders (irregular heartbeat, heart attack and stroke), eosinophilic pneumonia (a rare type of pneumonia), rhinitis (blocked up or runny nose), erythema multiforme, acute renal failure, changes in blood values such as a lower number of white and red blood cells, lower haemoglobin, lower number of blood platelets, inflammation of the pancreas (which causes severe pain in the abdomen and the back), hepatitis.
Not known (cannot be estimated from the available data): Raynaud's phenomenon.
Cases of SIADH have been reported with other ACE inhibitors. SIADH can be considered as a very rare but possible complication associated with ACE inhibitor therapy including perindopril.
Reporting of side effects: If the patient gets any side effects, talk to the doctor or pharmacist or nurse. This includes any possible side effects not listed in this monograph.
Report side effects directly via the national reporting system. By reporting side effects it can help provide more information on the safety of this medicine.